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KMID : 0381319920310040152
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Korean Journal of Occupational Health
1992 Volume.31 No. 4 p.152 ~ p.158
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Correlation Between the Ratio of Activated to Inactivated δ-Aminolevulinic Acid Dehydratase Activity(ALAD) Treated with Dithiothreitol and the Blood Lead Level in Highly Lead Exposed Workers
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Abstract
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The δ-aminolevulinic acid dehydratase activity (δ-ALAD) and the ration of activated to inactivated δ-ALAD treated with dithiothreitol of whole blood was measured to evaluate the correlation between the ratio and blood lead level
Zinc protoporphyrin (ZPP), the indices most widely used in screening of lead absorption and blood lead were also measured.
These parameters indicative of lead exposure were measured in whole blood from 57 highly lead exposed workers (most of them, ZPP was higher than 100㎍/100ml), and from a group of 15 control subjects not exposed to undue environmental lead.
We found that the correlation coefficient between the ratio and the blood lead level (r=0.58) was shghtly greater than the correlation cofficient between the log inactivated δ-ALAD and the blood lead level (r=0.51) among 57 highly lead exposed
workers.
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